Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
推荐稀释比 WB: 1/500-1/1000 IHC: 1/50-1/100
Western
Western blot analysis of SFN in RAW264.7, Hepg2, A431, 293T, A549 and Hela lysates using SFN antibody
Immunohistochemistry
Immunohistochemistry analysis of paraffin-embedded Human thyroid cancer using SFN antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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