Ouabain Octahydrate是一种 Na+/K+-ATPase 抑制剂,具有研究充血性心力衰竭的潜力。
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英文别名 (English Synonym) |
Ouabain Octahydrate |
|
中文名称 (Chinese Name) |
毒毛旋花苷G；乌本苷 |
|
靶点 (Target) |
Others |
|
通路 (Pathway) |
Others |
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CAS号 (CAS NO.) |
11018-89-6 |
|
分子式 (Formula) |
C29H60O20 |
|
分子量 (Molecular Weight) |
728.77 |
|
纯度 (Purity) |
≥95% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Venugopal J, McDermott J, Sanchez G, Sharma M, Barbosa L, Reif GA, Wallace DP, Blanco G. Ouabain promotes partial epithelial to mesenchymal transition (EMT) changes in human autosomal dominant polycystic kidney disease (ADPKD) cells. Exp Cell Res. 2017 Jun 15,355(2):142-152. doi: 10.1016/j.yexcr.2017.04.001. Epub 2017 Apr 3. PMID: 28385574, PMCID: PMC5497755.[2]Lima DB, Valente RC, Capella MA. Ouabain-induced alterations in ABCB1 of mesenteric lymph nodes and thymocytes of rats and mice. Oncol Lett. 2016 Dec,12(6):5275-5280. doi: 10.3892/ol.2016.5366. Epub 2016 Nov 8. PMID: 28105236, PMCID: PMC5228555.
