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Docetaxel Trihydrate，又称三水多西紫杉醇，紫杉醇类似物，是微管解聚的抑制剂，IC₅₀值为0.2 μM，通过诱导有丝分裂阻滞造成细胞凋亡，主要用作抗癌药物的合成中间体。

参考文献

[1] O'Hare T, Walters DK, Stoffregen EP, et al. In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants. Cancer Res. 2005 Jun 1;65(11):4500-5. doi: 10.1158/0008-5472(IF:8.378).

[2] Silvestrini R, Zaffaroni N, Orlandi L, et al. In vitro cytotoxic activity of Taxol and Taxotere on primary cultures and established cell lines of human ovarian cancer. Stem Cells. 1993 Nov;11(6):528-35. doi: 10.1002/stem.5530110622(IF:5.614).

[3] Moos PJ, Muskardin DT, Fitzpatrick FA, et al. Effect of taxol and taxotere on gene expression in macrophages: induction of the prostaglandin H synthase-2 isoenzyme. J Immunol. 1999 Jan 1;162(1):467-73(IF:4.7180).

-25~-15℃保存，有效期3年。