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Vonoprazan Fumarate，又称富马酸沃诺拉赞，是可口服的抗胃酸药物，是一种钾竞争性酸阻断剂，可以可逆抑制胃中H⁺/K⁺-ATPase，抑制胃酸分泌，临床上用于糜烂性食管炎、胃溃疡、十二指肠溃疡的治疗。

参考文献

[1] Arikawa Y, Nishida H, Kurasawa O, et al. Discovery of a novel pyrrole derivative 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate (TAK-438) as a potassium-competitive acid blocker (P-CAB). J Med Chem. 2012 May 10;55(9):4446-56. doi: 10.1021/jm300318t(IF:6.054).

[2] Hori Y, Imanishi A, Matsukawa J, et al. 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine monofumarate (TAK-438), a novel and potent potassium-competitive acid blocker for the treatment of acid-related diseases. J Pharmacol Exp Ther. 2010 Oct;335(1):231-8. doi: 10.1124/jpet.110.170274(IF:3.615).

-25~-15℃保存，有效期3年。