永利3044(中国集团)有限公司官网

Tanshinone IIA sulfonate sodium，又称丹参酮IIA-磺酸钠，是tanshinone IIA的水溶性衍生物，是从中草药丹参的干燥根中分离出来的天然化合物，用于治疗心血管疾病，是P2X7受体负变构调节剂，也是SOCE (store-operated Ca²⁺ entry)的抑制剂。STS通过下调TRPC的表达调节SOCC来抑制SOCE。

参考文献

[1] Chen D, Lin XX, Huang WH, et, al. Sodium tanshinone IIA sulfonate and its interactions with human CYP450s. Xenobiotica. 2016 Dec;46(12):1085-1092. doi: 10.3109/00498254.2016.1152417(IF:1.902).

[2] Ouyang DS, Huang WH, Chen D, et, al. Kinetics of cytochrome P450 enzymes for metabolism of sodium tanshinone IIA sulfonate in vitro. Chin Med. 2016 Mar 22;11:11. doi: 10.1186/s13020-016-0083-z(IF:2.265).

[3] Xu QQ, Xu YJ, Yang C, et, al. Sodium Tanshinone IIA Sulfonate Attenuates Scopolamine-Induced Cognitive Dysfunctions via Improving Cholinergic System. Biomed Res Int. 2016;2016:9852536. doi: 10.1155/2016/9852536(IF:2.197).

-25~-15℃保存，有效期3年。