STAT6 protein is a transcription factor activated by cytokines, particularly interleukin 4 and IL 13. (STAT6-/-) were found to be deficient in IL 4 mediated functions including Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL 4 mediated proliferation. STAT6 mRNA has been detected in peripheral bloodlymphocytes, colon, intestine, ovary, prostate,thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response.
推荐稀释比 WB:1/500-1/2000; IHC:1/100-1/300; IF:1/50-1/200; ELISA:1/10000
Western blot analysis of Phospho-STAT6 (Tyr641) in Hela lysates using Phospho-STAT6 (Tyr641) antibody.
Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using STAT6(Phospho-Tyr641) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.
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