This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
推荐稀释比 WB:1/500-1/1000; IHC:1/50-1/100
Western blot analysis of Bcl2 in MCF-7 lysates using Bcl2 antibody.
Western blot analysis of Bcl2 in K562, CHO-K1, 3T3, Hela lysates using Bcl2 antibody.
Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Bcl2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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