CD69 is a 27-33 kD type II transmembrane protein also known as activation inducer molecule (AIM), very early activation antigen (VEA), and MLR3. It is a member of the C-type lectin family, expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94, and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte, and platelet activation, and has a functional role in redirected lysis mediated by activated NK cells.
推荐稀释比 FC:5μL per test for million cells or whole blood in 100 μL volume.
Flow Cytometry analysis of PMA and ionomycinstimulated (4h) Jurkat cells stained with PE CD69 antibody (filled gray histogram) or mouse IgG1 Isotype Control PE (empty black histogram).
-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。
