CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
推荐稀释比 FC:5μL per test for million cells or whole blood in 100 μL volume.
Flow Cytometry analysis of C57BL/6 murine splenocytes stained with CD80 antibody (APC).Unstained splenocytes (empty black histogram) are used as control.
-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。
