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GRP94 Mouse mAb
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产品介绍

Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10.

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产品特色

推荐稀释比 WB:1/500-1/1000

应用案例

Western blot analysis of GRP94 in lysates of HeLa,293,HepG2 and MCF-7 using GRP94 antibody.

存储条件

-25 ~ -15℃保存,收到货之后有效期1年,避免反复冻融。

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