Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.
推荐稀释比 WB:1/500-1/1000;IP:1/20
Western blot analysis of IL-1RAcP in HL-60, U251, U87-MG lysates using IL-1 Receptor Accessory Protein antibody.
-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。
