The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.
推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100
Western blot analysis of IL-7 in Human kidney and mouse kidney lysates using IL-7 antibody.
Immunohistochemistry analysis of paraffin-embedded Human thyroid cancer using IL-7 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。
