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Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of COPS3 in NIH/3T3 lysates using COPS3 antibody.

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using COPS3 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。