This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene.
推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of ASAH1 in Human colon cancer, Human fetal brain, Human fetal lung lysates using ASAH1 antibody

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using ASAH1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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