Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Western
Western blot analysis of Bad in rat Brain, C6, 3T3, Hela lysates using Bad antibody.
Immunohistochemistry
Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Bad antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunocytochemistry
Immunocytochemistry analysis of Bad(green) in Hela using Bad antibody,and DAPI(blue)
-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。
