2-Hydroxylation of Fatty Acids Represses Colorectal Tumorigenesis and Metastasis via the YAP Transcriptional Axis
Sun Liang, Yang Xiaoqin, Huang Xiaoheng, Yao Yizhou, Wei Xiangyu, Yang Shugao, Zhou Diyuan, Zhang Wei, Long Zhimin, Xu Xiaoyan, Zhu Xinguo, He Songbing, Su Xiong
Journal：CANCER RESEARCH
IF：12.7
DOI：10.1158/0008-5472.CAN-20-1517
PMID：33203703
Published：2021-01-15
research field：药物毒理学生物信息学计算生物学肝脏病学网络毒理学分子药理学实验肝病学
Abstract
These findings identify a novel metabolic mechanism regulating the tumor suppressor function of FA 2-hydroxylation in colorectal cancer.
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